Chemotherapy-associated liver injury in colorectal cancer

Chemotherapy-associated liver injury in colorectal cancer

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Patients with colorectal cancer (CRC) have benefited significantly from advances in multimodal treatment with significant improvements in long-term survival.More patients are currently being treated with surgical resection orange zinger tomato or ablation following neoadjuvant or adjuvant chemotherapy.However, several cytotoxic agents that are administered routinely have been linked to liver toxicities that impair liver function and regeneration.Recognition of chemotherapy-related liver toxicity emphasizes the importance of chiggate.com multidisciplinary planning to optimize care.This review aims to summarize current data on multimodal treatment concepts for CRC, provide an overview of liver damage caused by commonly administered chemotherapeutic agents, and evaluate currently suggested protective agents.